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CRYOTOP®

Achieve the highest survival rates on the market with the Cryotop® Method, the global leader in vitrification of oocytes and embryos in all stages of development.

The revolutionary device by Kitazato has been applied in over 1,500,000 clinical cases for oocytes and embryos with this method of cryopreservation during the last decade, obtaining excellent results in over 90 countries and 2,200 assisted reproduction centres. The Cryotop® method is simple, safe, universal and easy to apply for everyone.

Cryotop® is a vitrification device consisting of a fine strip of transparent film attached to a plastic handle resistent to liquid nitrogen. Its design allows the loading of specimens for vitrification with a minimum volume (0.1 µl), providing the best Cooling and Warming rates on the market (-23,000ºC/minute and 42,000ºC/minute respectively) which in turn lead to the best survival rates.

Cryotop® statistics

Highest survival rates

Cryotop® Method offers proof of its outstanding results. Our suvival rates over 90% are backed up by numerous clinical studies with the biggest sample sizes in the market.

  • 100%
  • 90%
  • 80%
  • 70%
  • 60%
  • 50%
  • 40%
  • 30%
  • 20%
  • 10%
  • 0%
  • Oocytesn=3.286
    Cobo
    2010
  • Oocytesn=124
    Rienzi
    2010
  • Oocytesn=168
    Parmegiani
    2011
  • Oocytesn=898
    Solé
    2013
  • Embryosn=124
    Rienzi
    2012
  • Embryosn=168
    Parmegiani
    2012
  • Embryosn=898
    Solé
    2013
  • Blastocystsn=168
    Parmegiani
    2011
  • Blastocystsn=898
    Solé
    2012

Cryotop® Survival rates in human specimen

Main characteristics:

  • Allows up to 4 specimens to be loaded per device.
  •  It has an external covering to protect the Cryotop® once vitrified. Tip with weight to prevent floating in liquid nitrogen.
  • Manufactured in malleable plastic resistant to liquid nitrogen.
  • Available in packs of 10 units.

Cryotop® is the logical choice for obtaining the best clinical results. Its unparalleled survival rates for oocytes and embryos have contributed to bringing hundreds of healthy babies into the world in the last decade.

Accessories

Repro plate
Exclusively designed to follow the vitrification protocol with comfort; offers two slots to support the Cryotop®, allowing those who wish to carry out loading specimens statically. Has a flat base which allows the use of traceability labels.

Cooling rack
Designed to contain the liquid nitrogen during vitrification. Metallic cover for the interior also available, allowing sterilisation before use.

  • Endotoxin: ≤ 0.5EU/device by LAL methodology
  • Sterility (Bacteria, Fungi): current USP Sterility Test <71>
  • MEA (Mouse Embryo Assay): One cell assay ≥ 80% after 96 hours

Instructions


ORDER NUMBER CODE DESCRIPTION
81115 CR-Y Cryotop® Yellow
81114 CR-B Cryotop® Blue
81113 CR-W Cryotop® White
81112 CR-R Cryotop® Red
81111 CR-G Cryotop® Green
K Reproplate
94123 SET RACK-L Cooling Rack+Steel Box-Large
94122 SET RACK-S Cooling Rack+Steel Box-Short
91101 VT601 Vitrification Solutions *
91121 VT602 Thawing Solutions *
91171 VT801 Vitrification Solutions
91182 VT802 Thawing Solutions
81125 CR SC-Y Cryotop® SC Yellow
81124 CR SC-B Cryotop® SC Blue
81123 CR SC-W Cryotop® SC White
81122 CR SC-R Cryotop® SC Red
81121 CR SC-G Cryotop® SC Green
84115 BLOCK SC Aluminum Block for Cryotop® SC
84117 CUTTER SC Straw Cutter for Cryotop® SC
84119 HEAT SEALER Heat Sealer for Cryotop® SC
*These products are only available in selected countries

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