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From the 25th of May 2018 we will apply Regulation (EU) 2016/679 of the European Parliament and Council of the 27th of April 2016 with regard to the protection of personal data for natural persons. Consult our privacy policy here.


Cryotop® Method

Not just the best proven results on the market, now also the best user experience.

Achieve the highest survival rates on the market with the Cryotop® Method, the global leader in vitrification of oocytes and embryos in all stages of development.

The revolutionary device by Kitazato has been applied in over 1,500,000 clinical cases for oocytes and embryos with this method of cryopreservation during the last decade, obtaining excellent results in over 90 countries and 2,200 assisted reproduction centers. The Cryotop® method is simple, safe, universal and easy to apply for everyone.


New Cryotop® improvements

Wider Strip: The strip’s been widened. With a bigger surface, it is even easier to load the specimens.

Easier Insertion: The diamond tip, the reshaped conjunction between strip and handle and the widened body grant a smoother insertion into the cover straw.

Identification Marks: The Cryotop® has now two identification marks on its upper surface, defining the side where the specimens should be loaded, if you are vitrifying, or are loaded, if you are thawing.

Cryotop® is a vitrification device consisting of a fine strip of transparent film attached to a plastic handle resistant to liquid nitrogen. Its design allows the loading of specimens for vitrification with a minimum volume (0.1 µl), providing the best Cooling and Warming rates on the market (-23,000ºC/minute and 42,000ºC/minute respectively) which in turn lead to the best survival rates.

Cryotop® statistics
Vitification Cryotop

Main characteristics:

  • Allows up to 4 specimens to be loaded per device.
  •  It has an external covering to protect the Cryotop® once vitrified. Tip with weight to prevent floating in liquid nitrogen.
  • Manufactured in malleable plastic resistant to liquid nitrogen.
  • Available in packs of 10 units.

Highest survival rates

Cryotop® Method offers proof of its outstanding results. Our survival rates over 90% are backed up by numerous clinical studies with the biggest sample sizes in the market.

Cryotop® Survival rates in human specimen

  • 100%
  • 90%
  • 80%
  • 70%
  • 60%
  • 50%
  • 40%
  • 30%
  • 20%
  • 10%
  • 0%
  • Oocytesn=2.770
    Braga D.P.
  • Oocytesn=591
    Chamayou S.
  • Oocytesn=35.654
    Cornet-Bartolomé D.
  • Embryosn=303
    Xue Y.
  • Embryosn=2.617
    La Marca A.
  • Blastocystn=528
    Coello A.
  • Blastocystn=8.736
    Ueno S.
  • Blastocystn=3818
    Hernández-Nieto et al.
  • PGT Embryosn=90
    Sekhon L.
  • PGT Embryosn=2.129
    Cimadomo D.

In our publications section you will find the most relevant research on vitrification conducted using Kitazato products by IVF professionals and scientists from all over the world.

Cryotop® is the logical choice for obtaining the best clinical results. Its unparalleled survival rates for oocytes and embryos have contributed to bringing hundreds of healthy babies into the world in the last decade.


Repro Plate Cryotop® vitrification

Repro plate
Exclusively designed to follow the vitrification protocol with comfort; offers two slots to support the Cryotop®, allowing those who wish to carry out loading specimens statically. Has a flat base which allows the use of traceability labels.

Cooling Rack Cryotop® vitrification

Cooling rack
Designed to contain the liquid nitrogen during vitrification. Metallic cover for the interior also available, allowing sterilization before use.

81115 CR-Y Cryotop® Yellow
81114 CR-B Cryotop® Blue
81113 CR-W Cryotop® White
81112 CR-R Cryotop® Red
81111 CR-G Cryotop® Green
K Reproplate
94123 SET RACK-L Cooling Rack+Steel Box-Large
94122 SET RACK-S Cooling Rack+Steel Box-Short
91101 VT601 Vitrification Solutions*
91121 VT602 Thawing Solutions*
91171 VT801 Vitrification Solutions*
91182 VT802 Thawing Solutions*
81125 CR SC-Y Cryotop® SC Yellow
81124 CR SC-B Cryotop® SC Blue
81123 CR SC-W Cryotop® SC White
81122 CR SC-R Cryotop® SC Red
81121 CR SC-G Cryotop® SC Green
84115 BLOCK SC Aluminum Block for Cryotop® SC
84117 CUTTER SC Straw Cutter for Cryotop® SC
84119 HEAT SEALER Heat Sealer for Cryotop® SC
*These products are only available in selected countries

Fertility Preservation: Egg Banking: Embryos: Freeze-All: PGT: Safe Storage: See more relevant publications with the Cryotop® Method here

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